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Mesothelioma and Asbestos Exposure The people who use products containing asbestos are at risk of inhaling or ingesting asbestos fibers. The fibers are absorbed into the lining of the chest cavity or abdomen, also known as the pleura and peritoneum. The exposure to asbestos increases the chance of developing malignant pleural mesothelioma or peritoneal cancer throughout your life. Although the risk is believed to decrease after 40 years, asbestos exposure of any kind is dangerous. Age The older the person is when exposed, the greater the risk of developing mesothelioma. Mesothelioma can affect the mesothelium, an elongated layer that surrounds the major organs of the body. The cancerous cells are malignant, which means they grow out of control and develop into tumors. Mesothelioma is typically diagnosed in people who were exposed to asbestos, either through their own job or as a member of someone who was exposed to asbestos. Asbestos exposure can cause mesothelioma due to irritation of the mesothelium. The lung's lining (pleura) is most affected in people with mesothelioma of the pleural region, but it can also affect the abdomen's lining and peritoneum or the lining of the heart (pericardium). Asbestos is a non-porous and long-lasting mineral. It was used in construction, insulation and other industrial applications up to the 1980s. In this time millions of Americans were exposed to asbestos due to their jobs or by being close to a loved one. When asbestos is disturbed it releases fibers into air. They are too hard for the body's system to break them into pieces or process. The fibers can become stuck in the lungs, causing irritation that leads to cancer. Mesothelioma symptoms are typically not likely to appear until decades after exposure to asbestos. The symptoms are similar to those of other cancers, and they can be fatal if not treated. Men are more likely to be affected by mesothelioma more than women. It is also most often diagnosed for those who are older than 45. Miners, shipbuilders, railroad workers, and others who handled asbestos-containing products are at greatest risk of developing mesothelioma due to workplace asbestos exposure. Family members of these people are also at a higher risk because the asbestos can get on their clothing. Smoking The longer an individual is exposed to asbestos, the higher the chance of developing mesothelioma. This is because of the long time of latency which can range from 20 to 60 years from the first exposure until diagnosis. Mesothelioma can be found in various parts of the body depending on the type and quantity of asbestos present. Pleural mesothelioma is a condition that affects the lung's lining cavity and chest wall (the pleura). Peritoneal Mesothelioma is a condition that affects the abdomen's lining also known as the peritoneum. Most of the time, those who have been exposed develop mesothelioma that affects the chest or the lungs. The most at the risk are those who worked in the fields of shipbuilding, power production and construction. Mesothelioma can also be a risk for those who have been exposed at home or at school to asbestos. This is because children and spouses of workers who were exposed to asbestos could carry the asbestos fibers into their clothes hair, skin, and skin which can put them at risk of developing the disease. Mesothelioma sufferers are usually white and over 65. They are also more likely to hold a blue-collar position or military history. Asbestos was used extensively by the United States Navy and other branches in the military due to its flame-resistant qualities. Many veterans were exposed to asbestos. Mesothelioma can form when an individual's DNA undergoes mutations which cause cells to multiply uncontrolled. This may lead to development of tumors that eventually grow into mesothelioma. The disease can be affecting any part of the body, but most often it occurs in the chest or abdomen. Smoking is not a cause of mesothelioma. However, it increases the risk of this cancer by increasing the amount of asbestos that an individual inhales. Anyone who has been exposed asbestos should quit smoking cigarettes. Additionally, a person's mesothelioma treatment program should include an experienced doctor who is knowledgeable about asbestos exposure and the risk factors for this type of cancer. A specialist in mesothelioma who is knowledgeable to assist them determine the best approach to treat this rare cancer. The doctor will be able to determine whether a patient is eligible for immunotherapy or other experimental treatments. Asbestos Exposure Asbestos is a mineral that naturally occurs that is found in a myriad of products like roofing, flooring, and insulation. Anyone who works with asbestos-containing products make them, or manufacture them, or work with them are at a greater risk of being exposed. The exposure to asbestos fibers can result in breathing asbestos fibers into the lungs, where they can cause illness or cancer. There is a long time of time between exposure to asbestos and the onset of symptoms which makes it difficult to identify many asbestos-related diseases. Mesothelioma is the most deadly of asbestos diseases, is no exception. Mesothelioma symptoms can manifest between 20 and 60 years after asbestos exposure. The most frequent way in which people are exposed. All jobs that require asbestos handling or use include those in manufacturing, construction, automotive mechanics, and electrical. The risk of exposure to asbestos is also present through activities at home like smoking or renovating older houses that contain asbestos. Inhalation of asbestos is the most frequent mesothelioma causing agent. Inhaled asbestos fibers can travel to the lung, where they can cause irritation to the lining known as the pleura. This irritation leads to the formation of thickened pleura patches (pleural plaques) and fibrosis of the lungs. As the disease progresses, it can result in the accumulation of fluid in the chest cavity (pleural effusion) and eventually lung cancer. Mesothelioma can also affect the lining of other organs, including the heart and abdomen. Miami Beach asbestos lawsuits is the most frequent cancer among those who have been exposed to asbestos while at work. People with a history of family members or mesothelioma, or any other asbestos-related diseases are also at risk. The risk of exposure to asbestos is increased if a person has held more than one job in the course of their life. Smoking cigarettes can increase the risk of mesothelioma, but it can also aggravate the condition for those already diagnosed. Quitting smoking cigarettes is beneficial if you have a history of asbestos exposure and are suffering from mesothelioma. It will also allow you to live longer and enhance the results of your treatment. Inform your doctor if have been exposed to asbestos or notice any new symptoms such as abdominal pain or shortness of breathe. They can prescribe medication or operate to treat the disease. Genetics Many cancers are genetically linked which means that a person's genes may increase the likelihood of developing a specific disease. Mesothelioma, however not have a gene component. The exposure to asbestos is the main factor. Asbestos fibers can enter the body through swallowing or inhalation and adhere to the linings of the abdomen, chest or the heart. Over time, these loose fibers can cause damage or alteration to the cells that compose these linings. This can result in mesothelioma development. However, mesothelioma does not affect all people who are exposed. Researchers believe that other aspects can affect whether a person gets mesothelioma due to asbestos exposure. This includes age, gender, family history of mesothelioma and other illnesses, as in addition to any other risk factors like smoking. Men are more likely than women to develop mesothelioma. This may be because more men than women were exposed directly to asbestos at work. Mesothelioma is a cancer that can develop between 20 and 60 years after the first exposure to asbestos. A faulty gene is a second risk factor for mesothelioma. In a study that looked at two families with high rates of mesothelioma, researchers discovered that nearly every person in the family had a defective gene located on their short arm of chromosome 3. This gene is known as BAP 1 and regulates how calcium moves within cells. With a faulty gene the process is disrupted and calcium levels drop. This causes asbestos to transform healthy cells into cancerous ones and cause mesothelioma. Additionally the mutated gene within a person's immune system can also raise the chance of developing mesothelioma after exposure to asbestos. People with this mutated gene have a lower level of white blood cells, which are the cells that fight cancerous cells. Other factors that can raise a person's chance of mesothelioma include the type of asbestos they were exposed to as well as their work. Additionally the polio vaccine administered to children in the 1940s and 1950s could increase a person's mesothelioma risk because it exposed them to the cancer-causing SV40 virus.